Lung cancer, Tumor Cytogenetic and Roles of Telomeres with aging

Tumor antigens is an antigenic substance produced in tumor cells, it triggers an immune response in the host. Lung cancer is the most common cancer worldwide in both the indices of prevalence and mortality. Smoking is a risk factor highly associated with this type of cancer (85-90 %) and the exposure to tobacco smoke in the environment can cause cancer in nonsmokers. In genic therapy one procedure is introducing a genes into somatic human cells. Genic therapy in vivo in which the target cells are introduced directly into the body.2- Therapy ex vivo in which the target cells are modified in vitro and later replaced. Tumor cells exhibit non-random chromosome abnormalities. Recurrent in specific types of malignancies. Have been used as diagnostic and prognostic markers. Have lead to the understanding of biology of cancer. Telomeres are unique structures at the end of chromosomes are necessary for chromosomal integrity and overall genomic stability called as telomeres which protect genetic data, make it possible for cells to divide and hold some secrets to how grow old and et cancer.