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Formulation evaluation of bilayer tablet of saxagliptin & repaglinide

Formulation evaluation of bilayer tablet of saxagliptin & repaglinide

Anjali Soni / Dharmendra Solanki / PRIYANKA YADAV

84,34 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Farmacología
ISBN:
9786206144441
84,34 €
IVA incluido
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Bilayer tablet has been made and evaluated. For various precompression and post compression parameter. Precompression parameter shows that the granules and blends of repaglinide and saxagliptin have good Carr’s index and hausner’s ratio indicate that both granules and blends were free flowing. The angle of repose shows that granules and blends have excellent flow and post compression parameter show that bilayer tablet have thickness hardness and weight and friability within the I. P. limit and bilayer tablet have swelling index 82% in 6 hrs and have drug release first layer of saxagliptin release 98.6% in 30 minutes and second layer repaglinide release 95.5% in 12 hrs.

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