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Vue d’ensemble de la sclérose latérale amyotrophique

Vue d’ensemble de la sclérose latérale amyotrophique

Athar Talebi / Ilia Asadi / Pouya Saraei

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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Farmacología
ISBN:
9786205800386
92,35 €
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La sclérose latérale amyotrophique (SLA) est la maladie du motoneurone la plus répandue et une maladie neurologique progressive, invariablement mortelle, pour laquelle il n’existe aucune thérapie ou traitement viable permettant d’arrêter ou d’inverser la progression de la maladie. L’incidence globale de la maladie est de 2 à 3 pour 10 000 personnes et sa prévalence de 4 à 6 pour 100 000 personnes. Chaque année, la SLA touche environ 350 000 personnes dans le monde et en tue plus de 100 000. Elle porte le nom de Lou Gehrig, la star du baseball qui a contracté la maladie dans les années 1930. Pour une raison quelconque, l’étiologie de la maladie n’a pas encore été identifiée. La SLA est une maladie neurologique rare qui affecte principalement les cellules nerveuses et se définit par une paralysie musculaire progressive causée par la dégénérescence des motoneurones dans le cortex moteur, le tronc cérébral et la moelle épinière. Les motoneurones supérieurs (UMN) et les motoneurones inférieurs (LMN) s’atrophient dans la SLA et cessent de transmettre des messages aux muscles.

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