Bayya Subba Rao
“Pharmaceutical Research Methodology and Bio-Statistics: Theory and Practice” is aimed in understanding the fundamental concepts of developing a research bent of mind by careful planning, execution, collection of data and analyzing for statistical significance. The book is aimed at B. Pharm, Pharm D, Pharm D (PB), M. Pharm, allied course students, researchers at the academic and industry levels, Ph. D scholars, policy makers, regulators etc.· Exclusively relating to pharmaceuticals · Conventional English · Distinguishing statistics and bio-statistics· How to identify a problem, plan for research and execute the idea · Chemical abstract literature search · Anatomy of a research paper· Compare and contrast of research proposal, research report, research paper, patent document, synopsis · Concept of meta-analysis to resolve research ambiguities · Classification of clinical study designsApproaches of developing a research methodology · Abstract scaling concepts and techniques for developing questionnaire · Data collection, cleansing, presenting · How to overcome missing data Parametric distributions - binomial, poisson, normal, chi-square, student 't', F distributions · Role of Type I and Type II errors, Power, sample size, confidence level, confidence interval, confidence limits· How to judge whether data upon analysis is statistical significant or not · Developing hypothesis as null, alternate and how to draw conclusion after conducting suitable statistical test Non-parametric statistical test - Sign, Wilcoxon Signed rank, Wilcoxon rank sum tests Parametric, Non-parametric ANOVAs (1-way, 2-way, cross over)Step wise Parametric and non-parametric problem solving Statistical softwares like SPSS, SAS, Minitab, Epi-info with screenshotsApplications of linear regression and correlation coefficient relating to pharmaceuticalsFundamental concepts of book keeping, accountancy, emphasizing on making entries in journal and ledgerBasic terminology of epidemiologyInventory controlDeveloping a management report 3
