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Neutralização da hiperacidez gástrica pelos antiácidos

Neutralização da hiperacidez gástrica pelos antiácidos

Abdelali Merah / Leila Mekahlia / Youcef Hadef

93,50 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Farmacología
ISBN:
9786139764914
93,50 €
IVA incluido
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A hiperacidez gástrica, devida a uma produção excessiva de ácido clorídrico, pode provocar azia, dispepsia e refluxo gastro-esofágico. Os antiácidos minerais, como o hidróxido de alumínio, o hidróxido de magnésio e o carbonato de cálcio, neutralizam este excesso de ácido e aliviam os sintomas. Este estudo avaliou a capacidade de neutralização dos ácidos (CNA) de 13 antiácidos comercializados na Argélia, utilizando a titulação pH-métrica e o método titrimétrico. Os resultados mostraram que a maioria dos produtos excedia as normas da FDA, com Rennie (carbonato de cálcio e magnésio) a liderar, seguido de Maalox. A forma de dosagem influencia a eficácia, com os líquidos a superarem os comprimidos mastigáveis. Embora alguns produtos à base de alginato e bicarbonato tenham um ANC inferior, o seu mecanismo de proteção continua a ser relevante. O teor de sódio também deve ser considerado. Estes dados fornecem um guia para a escolha terapêutica e a direção da investigação futura.

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