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Mieloma múltiplo de idosos em reumatologia

Mieloma múltiplo de idosos em reumatologia

Afef Feki / Rim Akrout / Sofien Baklouti

61,57 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Medicina clínica e interna
ISBN:
9786205563540
61,57 €
IVA incluido
Disponible
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O mieloma múltiplo é uma proliferação maligna de células plasmáticas que segrega uma imunoglobulina monoclonal ou fragmento da mesma. O objectivo deste estudo é esclarecer as características clínicas, biológicas, radiológicas e terapêuticas da MM nos idosos. Foi realizada uma análise retrospectiva de 51 pacientes com MM com idade superior a 65 anos e seguidos num departamento de reumatologia durante um período de 22 anos. As circunstâncias da descoberta foram dominadas por dores ósseas (70,5%) e síndrome geral (50% dos casos). Na altura do diagnóstico, complicações hematológicas como a anemia eram mais frequentes neste contexto do que em outros. A maioria dos pacientes (90,1%) foram classificados como Salmão e Durie fase III. Os nossos pacientes foram tratados de acordo com 3 protocolos, dependendo do período de recrutamento. Quando seguimos os nossos pacientes, a maioria perdeu-se para o seguimento. As causas de morte foram dominadas pela toxicidade da quimioterapia. Assim, a gestão terapêutica destes pacientes requer uma avaliação da relação tolerância/eficácia para assegurar uma qualidade de vida adequada.

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