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Interações contentor-conteúdo

Interações contentor-conteúdo

Mohamed Hedi Ben Cheikh / Nour Elhouda Souissi

72,05 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786208537142
72,05 €
IVA incluido
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No sector farmacêutico, as interações recipiente-conteúdo referem-se à transferência de substâncias entre o equipamento de fabrico, a embalagem ou um dispositivo médico e o medicamento. Estes fenómenos incluem a adsorção de princípios activos ou excipientes nas paredes do recipiente, a sua penetração no interior dos materiais ou a sua difusão no ambiente externo. Além disso, estes fenómenos incluem a migração de substâncias do recipiente para o medicamento ou do ambiente externo para o medicamento.Estas interações podem comprometer a qualidade, eficácia e segurança dos produtos farmacêuticos, conduzindo a efeitos adversos potencialmente graves para os doentes, tais como alterações da eficácia terapêutica ou reacções tóxicas.Neste trabalho, relatamos exemplos de interações recipiente-conteúdo, especificando as circunstâncias em que ocorrem, as metodologias utilizadas para as estudar e o seu impacto no medicamento e no doente.

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