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ESTIMATIVA BIOANALÍTICA DO IMIQUIMOD NO PLASMA DE COELHO POR RP-HPLC

ESTIMATIVA BIOANALÍTICA DO IMIQUIMOD NO PLASMA DE COELHO POR RP-HPLC

Prachet Pinnamaneni

61,94 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2023
Materia
Farmacología
ISBN:
9786205866474
61,94 €
IVA incluido
Disponible
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O presente estudo centra-se na identificação e estimativa de fármacos na matriz biológica, utilizando uma técnica analítica sofisticada, estudando também os seus parâmetros farmacocinéticos como meias-vidas e taxas de eliminação e os seus metabolitos no sangue. O Imiquimod trata as verrugas externas em torno das áreas genital e rectal chamadas condiloma acuminatum. Existe uma relação directa entre a concentração do fármaco na fase biológica (local de acção) e a concentração do fármaco no plasma. Uma curva típica do tempo de concentração do fármaco no plasma, obtida após uma única dose oral de um fármaco e mostrando vários parâmetros farmacocinéticos e farmacodinâmicos.

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