A. Kishore Kumar / AKishore Kumar / P. Jalapathi / PJalapathi
This book describes a brief review on biological importance of 1,2,3-Triazoles and also provides the synthesis, characterization and biological study of some 1,4-disubstituted 1,2,3-Triazole heterocyclic molecules. It is divided into four chapters. The first chapter deals with the introduction and biological importance of 1,2,3-Triazole based heterocyclic compounds- a brief review. The second chapter describes the synthesis of some 1,2,3-Triazole derivatives. The third chapter deals with the synthesis of some Ibuprofen based 1,4-disubstituted 1,2,3-Triazoles. The fourth chapter describes the evaluation of anti-inflammatory activity of newly synthesized 1,2,3-Triazole derivatives. Structures of the compounds synthesized were established based on analytical and spectral data such as IR, 1H-NMR, 13C-NMR and MASS spectral data.
